SELANK

For Research Use Only | Not for Human or Veterinary Use

---

Description: Selank is a synthetic heptapeptide analogue of the endogenous immunomodulatory peptide tuftsin (Thr-Lys-Pro-Arg), extended at the C-terminus with a Pro-Gly-Pro stabilizing sequence. Developed at the Institute of Molecular Genetics of the Russian Academy of Sciences, Selank is investigated in preclinical laboratory research for its anxiolytic-like activity, immunomodulatory properties, and effects on neurotrophic factor expression. The C-terminal Pro-Gly-Pro extension confers enhanced metabolic stability and resistance to peptidase degradation compared to native tuftsin, making Selank a valuable research tool in neuroimmunology, GABAergic signaling studies, and stress-response pathway analysis.

---

Scientific Specifications:

• Peptide Name: Selank (Thr-Lys-Pro-Arg-Pro-Gly-Pro)
• Type: Synthetic Heptapeptide (Tuftsin Analogue)
• Sequence: Thr-Lys-Pro-Arg-Pro-Gly-Pro (TKPRPGP)
• Molecular Formula: C₃₃H₅₇N₁₁O₉
• Molecular Weight: 751.89 g/mol
• CAS Number: 129954-34-3
• PubChem CID: 11765600
• Form: Lyophilized powder
• Storage: Store dry in a cool, dark environment (2°C to 8°C)

---

Research Context: Selank is commonly studied for its potential effects on:

• GABAergic neurotransmission modulation and anxiolytic-like behavioral paradigms
• Brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF) expression regulation
• Innate and adaptive immune response modulation via tuftsin-related pathways
• Monoamine neurotransmitter metabolism (serotonin, dopamine, norepinephrine) in brain regions
• Stress-induced corticosterone response and HPA axis regulation in animal models
• Enkephalin and endorphin system interactions in nociceptive and emotional processing

---

Intended Use: This product is intended strictly for laboratory research applications only by qualified scientific personnel. It is not approved for human or animal consumption, and may not be used in foods, drugs, supplements, cosmetics, or diagnostics.

---

Legal Disclaimer: The statements provided and this compound have not been evaluated by the U.S. Food and Drug Administration. No claims are made regarding diagnosis, treatment, or prevention of any disease. Use is restricted to qualified researchers operating in certified laboratory environments.

---

Terms of Sale: By purchasing this product, the buyer affirms they are a qualified researcher or institutional purchaser, fully responsible for proper handling, storage, and legal compliance.